We created the Thesaurus. The thesaurus we use in PharmaPendium is based on well known building blocks (FDA Approval Packages, Mosby’s, MedDRA, and RTECS) with additions based on content in the product when needed.

• For drug names, we use a drug thesaurus from Mosby’s Drug Consult and added some synonyms from EMTREE when needed.
• For adverse effects/toxicities, we use a thesaurus based on MedDRA (by ICH) with terms from FDA documents, Meyler’s, Mosby’s Drug Consult and RTECS mapped into the MedDRA hierarchy.